As the 2026 NFL season moves into its second week, a supercomputer has analyzed every matchup, offering its predictions for the slate of games. According to GiveMeSport, the model has forecast the outcome and score of every Week 2 fixture following an opening weekend that saw reigning Super Bowl champions Seattle Seahawks secure a narrow victory, alongside strong starts from the Buffalo Bills, San Francisco 49ers, and Kansas City Chiefs.
The Week 2 schedule kicks off on Thursday at Highmark Stadium in New York, with the Buffalo Bills hosting the Detroit Lions. The week concludes with the Los Angeles Rams welcoming the New York Giants, with GiveMeSport detailing the supercomputer’s predictions for the full slate of games.
Champions and contenders aim for 2-0
The Seattle Seahawks, who claimed the Super Bowl title in 2025, opened their 2026 campaign with a tight 13-10 win over the New England Patriots. According to GiveMeSport, Mike LaFleur’s side is predicted to continue its winning streak against the Arizona Cardinals, with the supercomputer projecting a 24-21 victory for Seattle. The Cardinals also won their Week 1 opener against the Los Angeles Chargers.
Other strong Week 1 performers are also tipped for success by the model, as reported by GiveMeSport. The Buffalo Bills, fresh off a victory against the Houston Texans, are predicted to dominate the Detroit Lions with a 31-17 scoreline.
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The Kansas City Chiefs, who saw Patrick Mahomes return to action in Week 1 for the first time since December to lead them past the Denver Broncos, are projected to defeat the Indianapolis Colts 28-23. Andy Reid will be hoping his side can build on that momentum and move to 2-0.
Meanwhile, GiveMeSport reports that the Baltimore Ravens are backed for another convincing victory. After an emphatic 41-23 win against the Indianapolis Colts, Baltimore are forecast to beat the New Orleans Saints 30-17. The Saints narrowly lost their Week 1 encounter with the Detroit Lions.
The Philadelphia Eagles also made a promising start despite their training camp descending into chaos. They secured a 24-22 win over the Washington Commanders in Week 1, with Jalen Hurts throwing three touchdown passes. According to GiveMeSport’s report on the supercomputer predictions, Philadelphia are expected to overcome the Tennessee Titans 30-17.
Teams seeking first victory or bounce-back wins
Several teams that stumbled in Week 1 are predicted to rebound. GiveMeSport notes that the New England Patriots, who were Super Bowl losers last season and fell to the Seahawks in Week 1, are projected to secure their first victory against the Pittsburgh Steelers, winning 24-20.
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The Green Bay Packers, led by Matt LaFleur, lost to the Minnesota Vikings in Week 1 but are predicted to respond by beating the New York Jets 21-17 at MetLife Stadium.
There are several other notable predictions for teams attempting to turn their fortunes around. According to GiveMeSport, the Houston Texans are backed to edge out the Cincinnati Bengals 27-24 despite losing to the Bills in their opening game.
The Los Angeles Chargers, with Jim Harbaugh at the helm, are forecast to defeat the Las Vegas Raiders 27-23 after their Week 1 loss to the Arizona Cardinals.
Both the Dallas Cowboys and Washington Commanders lost their opening games, but GiveMeSport’s reported supercomputer prediction has Brian Schottenheimer’s Cowboys winning their divisional clash 30-27.
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The Chicago Bears, coached by Ben Johnson, are projected to beat the Minnesota Vikings 31-27, while the Cleveland Browns and Tampa Bay Buccaneers are both searching for their first victory after Week 1 defeats. The supercomputer backs Tampa Bay to come out on top 24-16.
Elsewhere, the Atlanta Falcons, under Kevin Stefanski, are projected to beat the Carolina Panthers 27-20, with both teams having lost their Week 1 games.
Jaguars on the road amid transformation
The Jacksonville Jaguars secured an impressive 34-20 victory over the Cleveland Browns in Week 1 but now face a different challenge. Due to a massive $1.4 billion transformation of EverBank Stadium, they will play away from their home ground.
According to GiveMeSport, the supercomputer does not expect Jacksonville to maintain its perfect start. The Jaguars are predicted to suffer a 27-21 defeat against the Denver Broncos at Empower Field at Mile High, bringing their early winning run to an end.
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