Milsami Orhei represents a relatively recent addition to Moldovan football, having been founded in 2005. Based in the city of Orhei, the club plays its home matches at the Complexul Sportiv Raional, a venue that accommodates 3160 spectators.

As a club still in its formative years, Milsami Orhei is focused on building its history within the national game. Without a long tradition of major honours or a roster of widely recognized players, its journey is one of ongoing competition and the continuous effort to carve out a distinct place in Moldovan football.